Hard to crack: molecules need to penetrate into the interior of the viruses to destroy them.
Hepatitis A virus HAV
(nonenveloped virus)
Hepatitis A virus is a nonenveloped, icosahedral capsid (spherical shape) with single-stranded RNA genome. It belongs to the Picornaviridae family.
Orally transmitted, the virus may cause local infections of the intestinal epithelium, and then, after a short viraemic episode, attacks the liver, where it replicates and finally triggers hepatitis.
The main transmission path is direct or indirect contact with contaminated persons or objects.
» Necessary spectrum of antimicrobial activity
Virucidal
