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Hard to crack: molecules need to penetrate into the interior of the viruses to destroy them.

(nonenveloped virus)

Polyomavirus is a nonenveloped virus that has the shape of an icosahedral capsid (spherical) and belongs to the Polyomaviridae family. It is classified in BK virus (human polyomavirus 1), JC virus (human polyomavirus 2, JC polyomavirus, JCV) and Simian virus 40.

JCV leads to progressive multifocal leukoencephalopathy (PML – affection of the central nervous system); the BK virus causes tubulo-interstitial nephritis (kidney disease).

The main transmission path is direct or indirect contact with contaminated persons or objects.

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